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MYC–MAX heterodimerization is essential for the induction of major zygotic genome activation and subsequent preimplantation development
In mouse preimplantation development, zygotic genome activation (ZGA), which synthesizes new transcripts in the embryo, begins in the S phase at the one-cell stage, with major ZGA occurring especially at the late two-cell stage. Myc is a transcription factor expressed in parallel with ZGA, but its d...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10520005/ https://www.ncbi.nlm.nih.gov/pubmed/37749153 http://dx.doi.org/10.1038/s41598-023-43127-5 |