Cargando…

MYC–MAX heterodimerization is essential for the induction of major zygotic genome activation and subsequent preimplantation development

In mouse preimplantation development, zygotic genome activation (ZGA), which synthesizes new transcripts in the embryo, begins in the S phase at the one-cell stage, with major ZGA occurring especially at the late two-cell stage. Myc is a transcription factor expressed in parallel with ZGA, but its d...

Descripción completa

Detalles Bibliográficos
Autores principales: Yamamoto, Takuto, Wang, Haoxue, Sato, Hana, Honda, Shinnosuke, Ikeda, Shuntaro, Minami, Naojiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10520005/
https://www.ncbi.nlm.nih.gov/pubmed/37749153
http://dx.doi.org/10.1038/s41598-023-43127-5