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In vivo label-free optical signatures of chemotherapy response in human pancreatic ductal adenocarcinoma patient-derived xenografts

Pancreatic cancer is a devastating disease often detected at later stages, necessitating swift and effective chemotherapy treatment. However, chemoresistance is common and its mechanisms are poorly understood. Here, label-free multi-modal nonlinear optical microscopy was applied to study microstruct...

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Detalles Bibliográficos
Autores principales: Park, Jaena, Sorrells, Janet E., Chaney, Eric J., Abdelrahman, Amro M., Yonkus, Jennifer A., Leiting, Jennifer L., Nelson, Heidi, Harrington, Jonathan J., Aksamitiene, Edita, Marjanovic, Marina, Groves, Peter D., Bushell, Colleen, Truty, Mark J., Boppart, Stephen A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10520051/
https://www.ncbi.nlm.nih.gov/pubmed/37749184
http://dx.doi.org/10.1038/s42003-023-05368-y