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Rapid emergence and transmission of virulence-associated mutations in the oral poliovirus vaccine following vaccination campaigns
There is an increasing burden of circulating vaccine-derived polioviruses (cVDPVs) due to the continued use of oral poliovirus vaccine (OPV). However, the informativeness of routine OPV VP1 sequencing for the early identification of viruses carrying virulence-associated reversion mutations has not b...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10520055/ https://www.ncbi.nlm.nih.gov/pubmed/37749086 http://dx.doi.org/10.1038/s41541-023-00740-9 |