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Genome-wide enhancer-gene regulatory maps link causal variants to target genes underlying human cancer risk
Genome-wide association studies have identified numerous variants associated with human complex traits, most of which reside in the non-coding regions, but biological mechanisms remain unclear. However, assigning function to the non-coding elements is still challenging. Here we apply Activity-by-Con...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10520073/ https://www.ncbi.nlm.nih.gov/pubmed/37749132 http://dx.doi.org/10.1038/s41467-023-41690-z |