Genome-wide enhancer-gene regulatory maps link causal variants to target genes underlying human cancer risk

Genome-wide association studies have identified numerous variants associated with human complex traits, most of which reside in the non-coding regions, but biological mechanisms remain unclear. However, assigning function to the non-coding elements is still challenging. Here we apply Activity-by-Con...

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Detalles Bibliográficos
Autores principales: Ying, Pingting, Chen, Can, Lu, Zequn, Chen, Shuoni, Zhang, Ming, Cai, Yimin, Zhang, Fuwei, Huang, Jinyu, Fan, Linyun, Ning, Caibo, Li, Yanmin, Wang, Wenzhuo, Geng, Hui, Liu, Yizhuo, Tian, Wen, Yang, Zhiyong, Liu, Jiuyang, Huang, Chaoqun, Yang, Xiaojun, Xu, Bin, Li, Heng, Zhu, Xu, Li, Ni, Li, Bin, Wei, Yongchang, Zhu, Ying, Tian, Jianbo, Miao, Xiaoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10520073/
https://www.ncbi.nlm.nih.gov/pubmed/37749132
http://dx.doi.org/10.1038/s41467-023-41690-z

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