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GPER deletion triggers inhibitory effects in triple negative breast cancer (TNBC) cells through the JNK/c-Jun/p53/Noxa transduction pathway

The G protein-coupled estrogen receptor (GPER) mediates estrogen action in different pathophysiological conditions, including cancer. GPER expression and signaling have been found to join in the progression of triple-negative breast cancer (TNBC), even though controversial data have been reported. I...

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Detalles Bibliográficos
Autores principales: Cirillo, Francesca, Talia, Marianna, Santolla, Maria Francesca, Pellegrino, Michele, Scordamaglia, Domenica, Spinelli, Asia, De Rosis, Salvatore, Giordano, Francesca, Muglia, Lucia, Zicarelli, Azzurra, Di Dio, Marika, Rigiracciolo, Damiano Cosimo, Miglietta, Anna Maria, Filippelli, Gianfranco, De Francesco, Ernestina Marianna, Belfiore, Antonino, Lappano, Rosamaria, Maggiolini, Marcello
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10520078/
https://www.ncbi.nlm.nih.gov/pubmed/37749101
http://dx.doi.org/10.1038/s41420-023-01654-0