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GPER deletion triggers inhibitory effects in triple negative breast cancer (TNBC) cells through the JNK/c-Jun/p53/Noxa transduction pathway
The G protein-coupled estrogen receptor (GPER) mediates estrogen action in different pathophysiological conditions, including cancer. GPER expression and signaling have been found to join in the progression of triple-negative breast cancer (TNBC), even though controversial data have been reported. I...
Autores principales: | Cirillo, Francesca, Talia, Marianna, Santolla, Maria Francesca, Pellegrino, Michele, Scordamaglia, Domenica, Spinelli, Asia, De Rosis, Salvatore, Giordano, Francesca, Muglia, Lucia, Zicarelli, Azzurra, Di Dio, Marika, Rigiracciolo, Damiano Cosimo, Miglietta, Anna Maria, Filippelli, Gianfranco, De Francesco, Ernestina Marianna, Belfiore, Antonino, Lappano, Rosamaria, Maggiolini, Marcello |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10520078/ https://www.ncbi.nlm.nih.gov/pubmed/37749101 http://dx.doi.org/10.1038/s41420-023-01654-0 |
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