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Targeting survivin with Tanshinone IIA inhibits tumor growth and overcomes chemoresistance in colorectal cancer

The inhibitor of apoptosis protein survivin has a critical regulatory role in carcinogenesis and treatment tolerance in colorectal cancer (CRC). However, the targeted drugs for survivin protein are extremely limited. In the present research, we discovered that Tanshinone IIA (Tan IIA) played a dual...

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Detalles Bibliográficos
Autores principales: Cao, Yaoquan, Tang, Haibo, Wang, Guohui, Li, Pengzhou, Song, Zhi, Li, Weizheng, Sun, Xulong, Zhong, Xiaoxiao, Yu, Qianqian, Zhu, Shaihong, Zhu, Liyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10520088/
https://www.ncbi.nlm.nih.gov/pubmed/37749082
http://dx.doi.org/10.1038/s41420-023-01622-8