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Targeting survivin with Tanshinone IIA inhibits tumor growth and overcomes chemoresistance in colorectal cancer
The inhibitor of apoptosis protein survivin has a critical regulatory role in carcinogenesis and treatment tolerance in colorectal cancer (CRC). However, the targeted drugs for survivin protein are extremely limited. In the present research, we discovered that Tanshinone IIA (Tan IIA) played a dual...
Autores principales: | Cao, Yaoquan, Tang, Haibo, Wang, Guohui, Li, Pengzhou, Song, Zhi, Li, Weizheng, Sun, Xulong, Zhong, Xiaoxiao, Yu, Qianqian, Zhu, Shaihong, Zhu, Liyong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10520088/ https://www.ncbi.nlm.nih.gov/pubmed/37749082 http://dx.doi.org/10.1038/s41420-023-01622-8 |
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