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Population Pharmacokinetic Analysis Supports Initiation Treatment and Bridging from Sublingual Buprenorphine to Subcutaneous Administration of a Buprenorphine Depot (CAM2038) in the Treatment of Opioid Use Disorder

BACKGROUND AND OBJECTIVE: In treating opioid use disorder (OUD), subcutaneous (SC) extended-release buprenorphine (BPN) depots, e.g., CAM2038, have been shown to provide smaller and less frequent fluctuations in BPN plasma concentrations and pharmacodynamic responses, improve outcomes, reduce treatm...

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Detalles Bibliográficos
Autores principales: Björnsson, Marcus, Acharya, Chayan, Strandgården, Kerstin, Tiberg, Fredrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10520114/
https://www.ncbi.nlm.nih.gov/pubmed/37584841
http://dx.doi.org/10.1007/s40262-023-01288-6