Population Pharmacokinetic Analysis of Dorzagliatin in Healthy Subjects and Patients with Type 2 Diabetes Mellitus

BACKGROUND AND OBJECTIVES: Dorzagliatin is a first-in-class small molecule glucokinase activator (GKA) that improves pancreatic insulin secretion behavior and regulates hepatic glucose conversion in a glucose concentration-dependent manner. The primary objective of this study was to develop a popula...

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Detalles Bibliográficos
Autores principales: Wang, Kun, Feng, Lingge, Zhang, Jiayi, Zou, Quanfei, Xu, Fengyan, Sun, Zhongyi, Tang, Fuxing, Chen, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10520121/
https://www.ncbi.nlm.nih.gov/pubmed/37537410
http://dx.doi.org/10.1007/s40262-023-01286-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10520121/
https://www.ncbi.nlm.nih.gov/pubmed/37537410
http://dx.doi.org/10.1007/s40262-023-01286-8

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