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Identification of phytochemical as a dual inhibitor of PI3K and mTOR: a structure-based computational approach
Breast cancer is a common form of cancer that affects both men and women. One of the most common types of genomic flaws in cancer is the aberrations in the PI3K/AKT/mTOR pathway. The benefit of dual targeting PI3K as well as mTOR is that the kinase-positive feedback loops are more effectively inhibi...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10520133/ https://www.ncbi.nlm.nih.gov/pubmed/36244040 http://dx.doi.org/10.1007/s11030-022-10541-2 |