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Identification of phytochemical as a dual inhibitor of PI3K and mTOR: a structure-based computational approach

Breast cancer is a common form of cancer that affects both men and women. One of the most common types of genomic flaws in cancer is the aberrations in the PI3K/AKT/mTOR pathway. The benefit of dual targeting PI3K as well as mTOR is that the kinase-positive feedback loops are more effectively inhibi...

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Detalles Bibliográficos
Autores principales: Kumar, B. Harish, Manandhar, Suman, Choudhary, Sneha Sunil, Priya, Keerthi, Gujaran, Tanvi V., Mehta, Chetan Hasmukh, Nayak, Usha Yogendra, Pai, K. Sreedhara Ranganath
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10520133/
https://www.ncbi.nlm.nih.gov/pubmed/36244040
http://dx.doi.org/10.1007/s11030-022-10541-2