Cargando…
Identification of phytochemical as a dual inhibitor of PI3K and mTOR: a structure-based computational approach
Breast cancer is a common form of cancer that affects both men and women. One of the most common types of genomic flaws in cancer is the aberrations in the PI3K/AKT/mTOR pathway. The benefit of dual targeting PI3K as well as mTOR is that the kinase-positive feedback loops are more effectively inhibi...
Autores principales: | Kumar, B. Harish, Manandhar, Suman, Choudhary, Sneha Sunil, Priya, Keerthi, Gujaran, Tanvi V., Mehta, Chetan Hasmukh, Nayak, Usha Yogendra, Pai, K. Sreedhara Ranganath |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10520133/ https://www.ncbi.nlm.nih.gov/pubmed/36244040 http://dx.doi.org/10.1007/s11030-022-10541-2 |
Ejemplares similares
-
Molecular dynamics and structure-based virtual screening and identification of natural compounds as Wnt signaling modulators: possible therapeutics for Alzheimer’s disease
por: Manandhar, Suman, et al.
Publicado: (2022) -
Structure-based docking, pharmacokinetic evaluation, and molecular dynamics-guided evaluation of traditional formulation against SARS-CoV-2 spike protein receptor bind domain and ACE2 receptor complex
por: kumar, B. Harish, et al.
Publicado: (2021) -
Computational drug repurposing of Akt-1 allosteric inhibitors for non-small cell lung cancer
por: Baby, Krishnaprasad, et al.
Publicado: (2023) -
Role of GSK-3β Inhibitors: New Promises and Opportunities for Alzheimer’s Disease
por: Shri, Suggala Ramya, et al.
Publicado: (2023) -
Advances in targeting EGFR allosteric site as anti-NSCLC therapy to overcome the drug resistance
por: Maity, Swastika, et al.
Publicado: (2020)