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PDE5 inhibitor drugs for use in dementia

Alzheimer's disease and related dementias (ADRD) remain a major health‐care challenge with few licensed medications. Repurposing existing drugs may afford prevention and treatment. Phosphodiesterase‐5 (PDE5) is widely expressed in vascular myocytes, neurons, and glia. Potent, selective, Food an...

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Detalles Bibliográficos
Autores principales: Hainsworth, Atticus H., Arancio, Ottavio, Elahi, Fanny M., Isaacs, Jeremy D., Cheng, Feixiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10520293/
https://www.ncbi.nlm.nih.gov/pubmed/37766832
http://dx.doi.org/10.1002/trc2.12412