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Novel exported fusion enzymes with chorismate mutase and cyclohexadienyl dehydratase activity: Shikimate pathway enzymes teamed up in no man's land

Chorismate mutase (CM) and cyclohexadienyl dehydratase (CDT) catalyze two subsequent reactions in the intracellular biosynthesis of l-phenylalanine (Phe). Here, we report the discovery of novel and extremely rare bifunctional fusion enzymes, consisting of fused CM and CDT domains, which are exported...

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Detalles Bibliográficos
Autores principales: Stocker, Christian, Khatanbaatar, Tamjidmaa, Bressan, Luca, Würth-Roderer, Kathrin, Cordara, Gabriele, Krengel, Ute, Kast, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10520331/
https://www.ncbi.nlm.nih.gov/pubmed/37586588
http://dx.doi.org/10.1016/j.jbc.2023.105161