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GDF15 Ameliorates Liver Fibrosis by Metabolic Reprogramming of Macrophages to Acquire Anti-Inflammatory Properties

BACKGROUND & AIMS: Liver fibrosis/cirrhosis is significant health burden worldwide, resulting in liver failure or cancer and accounting for many deaths each year. The pathogenesis of liver fibrosis is very complex, which makes treatment challenging. Growth differentiation factor 15 (GDF15), a cy...

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Detalles Bibliográficos
Autores principales: Li, Xiaolei, Huai, Qian, Zhu, Cheng, Zhang, Xu, Xu, Wentao, Dai, Hanren, Wang, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10520366/
https://www.ncbi.nlm.nih.gov/pubmed/37499753
http://dx.doi.org/10.1016/j.jcmgh.2023.07.009