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Inhibition of Abelson Tyrosine-Protein Kinase 2 Suppresses the Development of Alcohol-Associated Liver Disease by Decreasing PPARgamma Expression

BACKGROUND & AIMS: Alcohol-associated liver disease (ALD) represents a spectrum of alcohol use-related liver diseases. Outside of alcohol abstinence, there are currently no Food and Drug Administration–approved treatments for advanced ALD, necessitating a greater understanding of ALD pathogenesi...

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Detalles Bibliográficos
Autores principales: Malnassy, Greg, Keating, Claudia R., Gad, Shaimaa, Bridgeman, Bryan, Perera, Aldeb, Hou, Wei, Cotler, Scott J., Ding, Xianzhong, Choudhry, Mashkoor, Sun, Zhaoli, Koleske, Anthony J., Qiu, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10520367/
https://www.ncbi.nlm.nih.gov/pubmed/37460041
http://dx.doi.org/10.1016/j.jcmgh.2023.07.006