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An Improved Model for Circular RNA Overexpression: Using the Actin Intron Reveals High Circularization Efficiency
Traditionally, the group 1 intron of the T4 td gene is used to generate a foreign circular sequence. However, the T4 system has been shown to be fairly inefficient in expressing circular RNA (circRNA). Here, a new method is developed to express circular sequences with high circularization efficiency...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10520416/ https://www.ncbi.nlm.nih.gov/pubmed/37766804 http://dx.doi.org/10.1002/ggn2.202200019 |