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An Improved Model for Circular RNA Overexpression: Using the Actin Intron Reveals High Circularization Efficiency

Traditionally, the group 1 intron of the T4 td gene is used to generate a foreign circular sequence. However, the T4 system has been shown to be fairly inefficient in expressing circular RNA (circRNA). Here, a new method is developed to express circular sequences with high circularization efficiency...

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Detalles Bibliográficos
Autores principales: Li, Feiya, Lyu, Juanjuan, Yang, Yang, Yang, Qiwei, Santos, Cristian, Yang, Burton B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10520416/
https://www.ncbi.nlm.nih.gov/pubmed/37766804
http://dx.doi.org/10.1002/ggn2.202200019