A change point-based analysis procedure for improving the success rate of decision-making in clinical trials with delayed treatment effects

A delayed treatment effect is a commonly observed phenomenon in tumor immunotherapy clinical trials. It can cause a loss of statistical power and complicate the interpretation of the analytical findings. This phenomenon also poses challenges for interim analysis in the context of phase II/III seamle...

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Detalles Bibliográficos
Autores principales: Xie, Long-Shen, Lu, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10520459/
https://www.ncbi.nlm.nih.gov/pubmed/37767405
http://dx.doi.org/10.3389/fphar.2023.1186456

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10520459/
https://www.ncbi.nlm.nih.gov/pubmed/37767405
http://dx.doi.org/10.3389/fphar.2023.1186456

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