Cargando…

A change point-based analysis procedure for improving the success rate of decision-making in clinical trials with delayed treatment effects

A delayed treatment effect is a commonly observed phenomenon in tumor immunotherapy clinical trials. It can cause a loss of statistical power and complicate the interpretation of the analytical findings. This phenomenon also poses challenges for interim analysis in the context of phase II/III seamle...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xie, Long-Shen, Lu, Hui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10520459/ https://www.ncbi.nlm.nih.gov/pubmed/37767405 http://dx.doi.org/10.3389/fphar.2023.1186456

Ejemplares similares

Acute nicotine improves social decision-making in non-smoking but not in smoking schizophrenia patients
por: Quisenaerts, Charel, et al.
Publicado: (2013)

Sex-specific decision-making impairments and striatal dopaminergic changes after binge drinking history in rats
por: Sauton, Pierre, et al.
Publicado: (2023)

Pharmacoepidemiology Research-Real-World Evidence for Decision Making
por: Bérard, Anick
Publicado: (2021)

The Reliability and Relevance of a Quality of Decision Making Instrument, Quality of Decision-Making Orientation Scheme (QoDoS), for Use During the Lifecycle of Medicines
por: Bujar, Magdalena, et al.
Publicado: (2019)

Pivot Points: Five Decisions Every Successful Leader Must Make
por: Peters, Julia
Publicado: (2014)

Reimbursement decision-making system in Poland systematically compared to other countries
por: Mela, Aneta, et al.
Publicado: (2023)

The dilemma of antibiotic susceptibility and clinical decision-making in a multi-drug-resistant Pseudomonas aeruginosa bloodstream infection
por: Chen, Long, et al.
Publicado: (2023)

Reimbursement Legislations and Decision Making for Orphan Drugs in Central and Eastern European Countries
por: Malinowski, Krzysztof Piotr, et al.
Publicado: (2019)

Emerging Fluorescent Molecular Tracers to Guide Intra-Operative Surgical Decision-Making
por: Debie, Pieterjan, et al.
Publicado: (2019)

Editorial: Model-informed decision making in the preclinical stages of pharmaceutical research and development
por: Li, Rui, et al.
Publicado: (2023)

Shared decision making and medication adherence in patients with COPD and/or asthma: the ANANAS study
por: Achterbosch, Maria, et al.
Publicado: (2023)

Improving the Adherence to Antiretroviral Therapy, a Difficult but Essential Task for a Successful HIV Treatment—Clinical Points of View and Practical Considerations
por: Iacob, Simona A., et al.
Publicado: (2017)

The Development and Validation of a Generic Instrument, QoDoS, for Assessing the Quality of Decision Making
por: Donelan, Ronan, et al.
Publicado: (2016)

Navigating Between Right, Wrong, and Relevant: The Use of Mathematical Modeling in Preclinical Decision Making
por: Kondic, Anna, et al.
Publicado: (2022)

Contribution of patient registries to regulatory decision making on rare diseases medicinal products in Europe
por: Jonker, Carla J., et al.
Publicado: (2022)

Editorial: Shaping with data: Using pharmacoepidemiology to shape pharmaceutical policy and clinical decision-making
por: Tadrous, Mina, et al.
Publicado: (2022)

Humans Optimize Decision-Making by Delaying Decision Onset
por: Teichert, Tobias, et al.
Publicado: (2014)

Views of European Drug Development Stakeholders on Treatment Optimization and Its Potential for Use in Decision-Making
por: Saesen, Robbe, et al.
Publicado: (2020)

Design and Testing of an EHR-Integrated, Busulfan Pharmacokinetic Decision Support Tool for the Point-of-Care Clinician
por: Abdel-Rahman, Susan M., et al.
Publicado: (2016)

Using real-world data for supporting regulatory decision making: Comparison of cardiovascular and safety outcomes of an empagliflozin randomized clinical trial versus real-world data
por: Jang, Ha Young, et al.
Publicado: (2022)

Prognostic Nomogram for Early Gastric Cancer After Surgery to Assist Decision-Making for Treatment With Adjuvant Chemotherapy
por: Zhang, Chao, et al.
Publicado: (2022)

Efficacy, Safety, and Retention Rate of Extended-Release Divalproex Versus Conventional Delayed-Release Divalproex: A Meta-Analysis of Controlled Clinical Trials
por: Zhang, Chen Qi, et al.
Publicado: (2022)

Altered Cortico-Subcortical Network After Adolescent Alcohol Exposure Mediates Behavioral Deficits in Flexible Decision-Making
por: Gómez-A, Alexander, et al.
Publicado: (2021)

Health Economic Data in Reimbursement of New Medical Technologies: Importance of the Socio-Economic Burden as a Decision-Making Criterion
por: Iskrov, Georgi, et al.
Publicado: (2016)

An in silico Model of T Cell Infiltration Dynamics Based on an Advanced in vitro System to Enhance Preclinical Decision Making in Cancer Immunotherapy
por: Lewin, Thomas D., et al.
Publicado: (2022)

An Integrated Pharmacological Counselling Approach to Guide Decision-Making in the Treatment with CDK4/6 Inhibitors for Metastatic Breast Cancer
por: Roncato, Rossana, et al.
Publicado: (2022)

Heart Rate Variability and Decision-Making: Autonomic Responses in Making Decisions
por: Forte, Giuseppe, et al.
Publicado: (2021)

The point of normative models in judgment and decision making
por: Baron, Jonathan
Publicado: (2012)

Reimbursement of Orphan Drugs in Europe in Relation to the Type of Authorization by the European Medicines Agency and the Decision Making Based on Health Technology Assessment
por: Malinowski, Krzysztof Piotr, et al.
Publicado: (2018)

Evaluating Quality of Decision-Making Processes in Medicines' Development, Regulatory Review, and Health Technology Assessment: A Systematic Review of the Literature
por: Bujar, Magdalena, et al.
Publicado: (2017)

Big Data and Real-World Data based Cost-Effectiveness Studies and Decision-making Models: A Systematic Review and Analysis
por: Lu, Z. Kevin, et al.
Publicado: (2021)

Identification of high-risk patients for referral through machine learning assisting the decision making to manage minor ailments in community pharmacies
por: Amador-Fernández, Noelia, et al.
Publicado: (2023)

A Decision Procedure for String to Code Point Conversion
por: Reynolds, Andrew, et al.
Publicado: (2020)

Corrigendum: Big Data and Real-World Data Based Cost-Effectiveness Studies and Decision-Making Models: A Systematic Review and Analysis
por: Lu, Z. Kevin, et al.
Publicado: (2022)

Can Real-World Evidence Help Restore Decades of Health Inequalities by Informing Health Care Decision-Making? Certainly, and Here is How
por: Sarri, Grammati
Publicado: (2022)

The hippocampus encodes delay and value information during delay-discounting decision making
por: Masuda, Akira, et al.
Publicado: (2020)

Effects of individual and dyadic decision-making and normative reference on delay discounting decisions
por: Schwenke, Diana, et al.
Publicado: (2022)

Applying Theory of Planned Behavior to Understand Physicians’ Shared Decision-Making With Patients With Acute Respiratory Infections in Primary Care: A Cross-Sectional Study
por: Wang, Dan, et al.
Publicado: (2022)

Evaluation of the effectiveness and efficiency of the East African community joint assessment procedure by pharmaceutical companies: Opportunities for improvement
por: Ngum, Nancy, et al.
Publicado: (2022)

Risky Decision-Making but Not Delay Discounting Improves during Inpatient Treatment of Polysubstance Dependent Alcoholics
por: De Wilde, Bieke, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_0v4a5bujr5j1175t7uigjm4mat