α-(Aminomethyl)acrylates as acceptors in radical–polar crossover 1,4-additions of dialkylzincs: insights into enolate formation and trapping

We demonstrate that α-(aminomethyl)acrylates are suitable acceptors for 1,4-additions of dialkylzincs in aerobic conditions. The air-promoted radical–polar crossover process involves the 1,4-addition of an alkyl radical followed by homolytic substitution at the zinc atom of dialkylzinc. Coordination...

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Detalles Bibliográficos
Autores principales: Palillero-Cisneros, Angel, Gordillo-Guerra, Paola G, García-Alvarez, Fernando, Jackowski, Olivier, Ferreira, Franck, Chemla, Fabrice, Terán, Joel L, Perez-Luna, Alejandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2023
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10520473/
https://www.ncbi.nlm.nih.gov/pubmed/37767333
http://dx.doi.org/10.3762/bjoc.19.103

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10520473/
https://www.ncbi.nlm.nih.gov/pubmed/37767333
http://dx.doi.org/10.3762/bjoc.19.103

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