Glycolytic enzyme PKM2 regulates cell senescence but not inflammation in the process of osteoarthritis: PKM2 regulates chondrocyte senescence via p16 (INK4a) transcription

Chondrocyte senescence is an important mechanism underlying osteoarthritis in the senile population and is characterized by reduced expressions of the extracellular matrix proteins. The involvement of glycolysis and the tricarboxylic acid cycle in the development of osteoarthritis is inclusive. The...

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Detalles Bibliográficos
Autores principales: Liu, Bo, Wang, Chenzhong, Weng, Ziyu, Yang, Yi, Zhao, Hong, Zhang, Yueqi, Fei, Qinming, Shi, Yi, Zhang, Chi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10520488/
https://www.ncbi.nlm.nih.gov/pubmed/37525533
http://dx.doi.org/10.3724/abbs.2023062

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10520488/
https://www.ncbi.nlm.nih.gov/pubmed/37525533
http://dx.doi.org/10.3724/abbs.2023062

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