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Role of heat shock protein 47 in platelet glycoprotein VI dimerization and signaling

BACKGROUND: Heat shock protein 47 (HSP47) is an intracellular chaperone protein with an indispensable role in collagen biosynthesis in collagen-secreting cells. This chaperone has also been shown to be released and present on the surface of platelets. The inhibition of HSP47 in human platelets or it...

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Detalles Bibliográficos
Autores principales: AlOuda, Sarah K., Sasikumar, Parvathy, AlThunayan, Taysseer, Alaajam, Fahd, Khan, Sabeeya, Sahli, Khaled A., Abohassan, Mohammed S., Pollitt, Alice, Jung, Stephanie M., Gibbins, Jonathan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10520510/
https://www.ncbi.nlm.nih.gov/pubmed/37767064
http://dx.doi.org/10.1016/j.rpth.2023.102177