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A hypothermia mimetic molecule (zr17-2) reduces ganglion cell death, gliosis, and electroretinogram distortion in male rats subjected to perinatal asphyxia

Introduction: Perinatal asphyxia (PA) represents a major problem in perinatology and may cause visual losses, including blindness. We, and others, have shown that hypothermia prevents retinal symptoms associated to PA. In the present work, we evaluate whether a hypothermia mimetic small molecule, zr...

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Detalles Bibliográficos
Autores principales: Rey-Funes, Manuel, Fernández, Juan Carlos, Peláez, Rafael, Soliño, Manuel, Contartese, Daniela S., Ciranna, Nicolás S., Nakamura, Ronan, Sarotto, Aníbal, Dorfman, Verónica B., Zapico, José M., Ramos, Ana, de Pascual-Teresa, Beatriz, López-Costa, Juan José, Larrayoz, Ignacio M., Martínez, Alfredo, Loidl, César Fabián
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10520548/
https://www.ncbi.nlm.nih.gov/pubmed/37767403
http://dx.doi.org/10.3389/fphar.2023.1252184