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DNA-dependent protein kinase catalytic subunit (DNA-PKcs) drives angiotensin II-induced vascular remodeling through regulating mitochondrial fragmentation

BACKGROUND: DNA-dependent protein kinase catalytic subunit (DNA-PKcs) is a novel instigator for mitochondrial dysfunction, and plays an important role in the pathogenesis of cardiovascular diseases. However, the role and mechanism of DNA-PKcs in angiotensin II (Ang II)-induced vascular remodeling re...

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Detalles Bibliográficos
Autores principales: Wang, Litao, Wu, Lin, Du, Yuxin, Wang, Xiang, Yang, Bingsheng, Guo, Shuai, Zhou, Yuan, Xu, Yiming, Yang, Shuofei, Zhang, Yingmei, Ren, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10520570/
https://www.ncbi.nlm.nih.gov/pubmed/37741045
http://dx.doi.org/10.1016/j.redox.2023.102893