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Targeting Alpha‐Ketoglutarate Disruption Overcomes Immunoevasion and Improves PD‐1 Blockade Immunotherapy in Renal Cell Carcinoma

The Warburg effect‐related metabolic dysfunction of the tricarboxylic acid (TCA) cycle has emerged as a hallmark of various solid tumors, particularly renal cell carcinoma (RCC). RCC is characterized by high immune infiltration and thus recommended for immunotherapeutic interventions at an advanced...

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Detalles Bibliográficos
Autores principales:	Li, Le, Zeng, Xing, Chao, Zheng, Luo, Jing, Guan, Wei, Zhang, Qiang, Ge, Yue, Wang, Yanan, Xiong, Zezhong, Ma, Sheng, Zhou, Qiang, Zhang, Junbiao, Tian, Jihua, Horne, David, Yuh, Bertram, Hu, Zhiquan, Wei, Gong‐Hong, Wang, Baojun, Zhang, Xu, Lan, Peixiang, Wang, Zhihua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2023
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10520657/ https://www.ncbi.nlm.nih.gov/pubmed/37526345 http://dx.doi.org/10.1002/advs.202301975

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