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High throughput clone screening on overexpressed hERG1 and Kv1.3 potassium channels using ion channel reader (ICR) label free technology

Pharmacological studies aimed at the development of newly synthesized drugs directed against ion channels (as well as genetic studies of ion channel mutations) involve the development and use of transfected cells. However, the identification of the best clone, in terms of transfection efficiency, is...

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Detalles Bibliográficos
Autores principales: Montalbano, Alberto, Sala, Cesare, Altadonna, Ginevra Chioccioli, Becchetti, Andrea, Arcangeli, Annarosa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10520782/
https://www.ncbi.nlm.nih.gov/pubmed/37767500
http://dx.doi.org/10.1016/j.heliyon.2023.e20112