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High throughput clone screening on overexpressed hERG1 and Kv1.3 potassium channels using ion channel reader (ICR) label free technology
Pharmacological studies aimed at the development of newly synthesized drugs directed against ion channels (as well as genetic studies of ion channel mutations) involve the development and use of transfected cells. However, the identification of the best clone, in terms of transfection efficiency, is...
Autores principales: | Montalbano, Alberto, Sala, Cesare, Altadonna, Ginevra Chioccioli, Becchetti, Andrea, Arcangeli, Annarosa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10520782/ https://www.ncbi.nlm.nih.gov/pubmed/37767500 http://dx.doi.org/10.1016/j.heliyon.2023.e20112 |
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