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APOLLO, a testis-specific Drosophila ortholog of importin-4, mediates the loading of protamine-like protein Mst77F into sperm chromatin

DNA in sperm is packed with small, charged proteins termed SNBPs (sperm nuclear basic proteins), including mammalian and Drosophila protamines. During spermiogenesis, somatic-type chromatin is taken apart and replaced with sperm chromatin in a multistep process leading to an extraordinary condensati...

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Detalles Bibliográficos
Autores principales: Emelyanov, Alexander V., Barcenilla-Merino, Daniel, Loppin, Benjamin, Fyodorov, Dmitry V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10520872/
https://www.ncbi.nlm.nih.gov/pubmed/37660905
http://dx.doi.org/10.1016/j.jbc.2023.105212