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Golgi α-mannosidases regulate cell surface N-glycan type and ectodomain shedding of the transmembrane protease corin
Corin is a transmembrane protease that activates natriuretic peptides on the cell membrane. Reduced cell surface targeting or increased ectodomain shedding disrupts cell membrane homeostasis of corin, thereby impairing its cell surface expression and enzyme activity. N-glycans are essential in corin...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10520876/ https://www.ncbi.nlm.nih.gov/pubmed/37660903 http://dx.doi.org/10.1016/j.jbc.2023.105211 |