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Golgi α-mannosidases regulate cell surface N-glycan type and ectodomain shedding of the transmembrane protease corin

Corin is a transmembrane protease that activates natriuretic peptides on the cell membrane. Reduced cell surface targeting or increased ectodomain shedding disrupts cell membrane homeostasis of corin, thereby impairing its cell surface expression and enzyme activity. N-glycans are essential in corin...

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Detalles Bibliográficos
Autores principales: Wang, Hao, Liu, Yi-Shi, Peng, Yingfei, Chen, Wei, Dong, Ningzheng, Wu, Qingyu, Pan, Baishen, Wang, Beili, Guo, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10520876/
https://www.ncbi.nlm.nih.gov/pubmed/37660903
http://dx.doi.org/10.1016/j.jbc.2023.105211