Highly multiplexed spatial analysis identifies tissue-resident memory T cells as drivers of ulcerative and immune checkpoint inhibitor colitis

Colitis is a prevalent adverse event associated with immune checkpoint inhibitor (ICI) therapy with similarities to inflammatory bowel disease. Incomplete mechanistic understanding of ICI colitis curtails evidence-based treatment. Given the often-overlooked connection between tissue architecture and...

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Detalles Bibliográficos
Autores principales: van Eijs, Mick J.M., ter Linde, José J.M., Baars, Matthijs J.D., Amini, Mojtaba, Laclé, Miangela M., Brand, Eelco C., Delemarre, Eveline M., Drylewicz, Julia, Nierkens, Stefan, Verheijden, Rik J., Oldenburg, Bas, Vercoulen, Yvonne, Suijkerbuijk, Karijn P.M., van Wijk, Femke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10520880/
https://www.ncbi.nlm.nih.gov/pubmed/37766980
http://dx.doi.org/10.1016/j.isci.2023.107891

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10520880/
https://www.ncbi.nlm.nih.gov/pubmed/37766980
http://dx.doi.org/10.1016/j.isci.2023.107891

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