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Porcine IKKε is involved in the STING-induced type I IFN antiviral response of the cytosolic DNA signaling pathway

The cyclic GMP–AMP synthase and stimulator of interferon (IFN) genes (cGAS–STING) pathway serves as a crucial component of innate immune defense and exerts immense antiviral activity by inducing the expression of type I IFNs. Currently, STING-activated production of type I IFNs has been thought to b...

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Detalles Bibliográficos
Autores principales: Luo, Jia, Cao, Qi, Zhang, Jiajia, Jiang, Sen, Xia, Nengwen, Sun, Shaohua, Zheng, Wanglong, Chen, Nanhua, Meurens, Francois, Zhu, Jianzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10520887/
https://www.ncbi.nlm.nih.gov/pubmed/37660925
http://dx.doi.org/10.1016/j.jbc.2023.105213