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Porcine IKKε is involved in the STING-induced type I IFN antiviral response of the cytosolic DNA signaling pathway
The cyclic GMP–AMP synthase and stimulator of interferon (IFN) genes (cGAS–STING) pathway serves as a crucial component of innate immune defense and exerts immense antiviral activity by inducing the expression of type I IFNs. Currently, STING-activated production of type I IFNs has been thought to b...
Autores principales: | Luo, Jia, Cao, Qi, Zhang, Jiajia, Jiang, Sen, Xia, Nengwen, Sun, Shaohua, Zheng, Wanglong, Chen, Nanhua, Meurens, Francois, Zhu, Jianzhong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10520887/ https://www.ncbi.nlm.nih.gov/pubmed/37660925 http://dx.doi.org/10.1016/j.jbc.2023.105213 |
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