GDF15 deficiency hinders human trophoblast invasion to mediate pregnancy loss through downregulating Smad1/5 phosphorylation

Growth differentiation factor 15 (GDF15) belongs to the Transforming growth factor β(TGF-β) superfamily. The decrease of GDF15 in the serum of pregnant women was associated with miscarriage. Both IHC and ELISA assays showed that GDF15 in trophoblast tissue and serum of pregnant women who miscarried...

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Detalles Bibliográficos
Autores principales: Zeng, Yu-Ting, Liu, Wen-Fang, Zheng, Peng-Sheng, Li, Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10520888/
https://www.ncbi.nlm.nih.gov/pubmed/37766993
http://dx.doi.org/10.1016/j.isci.2023.107902

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10520888/
https://www.ncbi.nlm.nih.gov/pubmed/37766993
http://dx.doi.org/10.1016/j.isci.2023.107902

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