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The endoplasmic reticulum–localized enzyme zDHHC6 mediates S-acylation of short transmembrane constructs from multiple type I and II membrane proteins

In this study, we investigated the S-acylation of two host cell proteins important for viral infection: TMPRSS2 (transmembrane serine protease 2), which cleaves severe acute respiratory syndrome coronavirus 2 spike to facilitate viral entry, and bone marrow stromal antigen 2, a general viral restric...

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Detalles Bibliográficos
Autores principales: Salaun, Christine, Tomkinson, Nicholas C.O., Chamberlain, Luke H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10520890/
https://www.ncbi.nlm.nih.gov/pubmed/37660915
http://dx.doi.org/10.1016/j.jbc.2023.105201