Toblerone: detecting exon deletion events in cancer using RNA-seq

Cancer is driven by mutations of the genome that can result in the activation of oncogenes or repression of tumour suppressor genes. In acute lymphoblastic leukemia (ALL) focal deletions in IKAROS family zinc finger 1 (IKZF1) result in the loss of zinc-finger DNA-binding domains and a dominant negat...

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Detalles Bibliográficos
Autores principales: Lonsdale, Andrew, Halman, Andreas, Brown, Lauren, Kosasih, Hansen, Ekert, Paul, Oshlack, Alicia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10521068/
https://www.ncbi.nlm.nih.gov/pubmed/37767021
http://dx.doi.org/10.12688/f1000research.129490.1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10521068/
https://www.ncbi.nlm.nih.gov/pubmed/37767021
http://dx.doi.org/10.12688/f1000research.129490.1

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