Checkpoint kinase interaction with DNA polymerase alpha regulates replication progression during stress

Background: In eukaryotes, replication stress activates a checkpoint response, which facilitates genome duplication by stabilising the replisome. How the checkpoint kinases regulate the replisome remains poorly understood. The aim of this study is to identify new targets of checkpoint kinases within...

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Detalles Bibliográficos
Autores principales: Hadjicharalambous, Andreas, Whale, Alex J., Can, Geylani, Skehel, J. Mark, Houseley, Jonathan M., Zegerman, Philip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10521137/
https://www.ncbi.nlm.nih.gov/pubmed/37766847
http://dx.doi.org/10.12688/wellcomeopenres.19617.1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10521137/
https://www.ncbi.nlm.nih.gov/pubmed/37766847
http://dx.doi.org/10.12688/wellcomeopenres.19617.1

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