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Checkpoint kinase interaction with DNA polymerase alpha regulates replication progression during stress
Background: In eukaryotes, replication stress activates a checkpoint response, which facilitates genome duplication by stabilising the replisome. How the checkpoint kinases regulate the replisome remains poorly understood. The aim of this study is to identify new targets of checkpoint kinases within...
Autores principales: | Hadjicharalambous, Andreas, Whale, Alex J., Can, Geylani, Skehel, J. Mark, Houseley, Jonathan M., Zegerman, Philip |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
F1000 Research Limited
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10521137/ https://www.ncbi.nlm.nih.gov/pubmed/37766847 http://dx.doi.org/10.12688/wellcomeopenres.19617.1 |
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