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Synthesis and application of spermine-based amphiphilic poly(β-amino ester)s for siRNA delivery
Small interfering RNA (siRNA) can trigger RNA interference (RNAi) to therapeutically silence disease-related genes in human cells. The approval of siRNA therapeutics by the FDA in recent years generated a new hope in novel and efficient siRNA therapeutics. However, their therapeutic application is s...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
RSC
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10521211/ https://www.ncbi.nlm.nih.gov/pubmed/37767040 http://dx.doi.org/10.1039/d3na00272a |