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Synthesis and application of spermine-based amphiphilic poly(β-amino ester)s for siRNA delivery

Small interfering RNA (siRNA) can trigger RNA interference (RNAi) to therapeutically silence disease-related genes in human cells. The approval of siRNA therapeutics by the FDA in recent years generated a new hope in novel and efficient siRNA therapeutics. However, their therapeutic application is s...

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Detalles Bibliográficos
Autores principales:	Jin, Yao, Adams, Friederike, Nguyen, Anny, Sturm, Sebastian, Carnerio, Simone, Müller-Caspary, Knut, Merkel, Olivia M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	RSC 2023
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10521211/ https://www.ncbi.nlm.nih.gov/pubmed/37767040 http://dx.doi.org/10.1039/d3na00272a

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