Box–Behnken design of thermo-responsive nano-liposomes loaded with a platinum(iv) anticancer complex: evaluation of cytotoxicity and apoptotic pathways in triple negative breast cancer cells

Herein, thermo-responsive liposomes (TLs) loaded with Asp (Asp/TLs) were produced by self-assembling DPPC, DSPE-PEG2000, and cholesterol. The preparation variables were optimized using the Box–Behnken design (BBD). The optimized Asp/TLs exhibited an average particle size of 114.05 ± 1.56 nm, PDI of...

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Detalles Bibliográficos
Autores principales: Sedky, Nada K., Braoudaki, Maria, Mahdy, Noha Khalil, Amin, Kenzy, Fawzy, Iten M., Efthimiadou, Eleni K., Youness, Rana A., Fahmy, Sherif Ashraf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10521260/
https://www.ncbi.nlm.nih.gov/pubmed/37767043
http://dx.doi.org/10.1039/d3na00368j

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10521260/
https://www.ncbi.nlm.nih.gov/pubmed/37767043
http://dx.doi.org/10.1039/d3na00368j

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