Cargando…

Box–Behnken design of thermo-responsive nano-liposomes loaded with a platinum(iv) anticancer complex: evaluation of cytotoxicity and apoptotic pathways in triple negative breast cancer cells

Herein, thermo-responsive liposomes (TLs) loaded with Asp (Asp/TLs) were produced by self-assembling DPPC, DSPE-PEG2000, and cholesterol. The preparation variables were optimized using the Box–Behnken design (BBD). The optimized Asp/TLs exhibited an average particle size of 114.05 ± 1.56 nm, PDI of...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sedky, Nada K., Braoudaki, Maria, Mahdy, Noha Khalil, Amin, Kenzy, Fawzy, Iten M., Efthimiadou, Eleni K., Youness, Rana A., Fahmy, Sherif Ashraf
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	RSC 2023
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10521260/ https://www.ncbi.nlm.nih.gov/pubmed/37767043 http://dx.doi.org/10.1039/d3na00368j

Ejemplares similares

A Snapshot of Photoresponsive Liposomes in Cancer Chemotherapy and Immunotherapy: Opportunities and Challenges
por: Youness, Rana A., et al.
Publicado: (2023)

Process optimization and modeling of Cd(2+) biosorption onto the free and immobilized Turbinaria ornata using Box–Behnken experimental design
por: Fawzy, Mustafa A., et al.
Publicado: (2022)

Optimization of Nasal Liposome Formulation of Venlafaxine Hydrochloride using a Box-Behnken Experimental Design
por: Khute, Sulekha, et al.
Publicado: (2023)

Oral Delivery of Psoralidin by Mucoadhesive Surface-Modified Bilosomes Showed Boosted Apoptotic and Necrotic Effects against Breast and Lung Cancer Cells
por: Youness, Rana Ahmed, et al.
Publicado: (2023)

Optimization of Paclitaxel Containing pH-Sensitive Liposomes By 3 Factor, 3 Level Box-Behnken Design
por: Rane, Smita, et al.
Publicado: (2013)

Green Synthesis of Platinum and Palladium Nanoparticles Using Peganum harmala L. Seed Alkaloids: Biological and Computational Studies
por: Fahmy, Sherif Ashraf, et al.
Publicado: (2021)

Development and Optimization of Ciprofloxacin HCl-Loaded Chitosan Nanoparticles Using Box–Behnken Experimental Design
por: Soliman, Noha M., et al.
Publicado: (2022)

Optimization of mirtazapine loaded into mesoporous silica nanostructures via Box-Behnken design: in-vitro characterization and in-vivo assessment
por: Musallam, Abeer A., et al.
Publicado: (2022)

Formulation and characterization of ketoprofen liquisolid compacts by Box-Behnken design
por: Vittal, G Vijayaranga, et al.
Publicado: (2012)

The application of Box-Behnken-Design in the optimization of HPLC separation of fluoroquinolones
por: Czyrski, Andrzej, et al.
Publicado: (2019)

Synthesis of Polyhydroxyurethanes—Experimental Verification of the Box–Behnken Optimization Model
por: Zalewski, Michał J., et al.
Publicado: (2022)

Rheological and Mechanical Analyses of Felbinac Cataplasms by Using Box–Behnken Design
por: Yang, Jie, et al.
Publicado: (2018)

Sorption studies of europium on cerium phosphate using Box-Behnken design
por: İNAN, Süleyman
Publicado: (2020)

Box–Behnken Design for Polycarbonate-Pigment Blending: Applications and Characterization Techniques
por: Alsadi, Jamal, et al.
Publicado: (2022)

Box–Behnken Design of Experiments of Polycaprolactone Nanoparticles Loaded with Irinotecan Hydrochloride
por: Mahmoud, Basant Salah, et al.
Publicado: (2023)

Optimization of the Poly(glycerol citraconate) Synthesis Using the Box–Behnken Design
por: Kolankowski, Krzysztof, et al.
Publicado: (2023)

Fermentation-Assisted Extraction of Isothiocyanates from Brassica Vegetable Using Box-Behnken Experimental Design
por: Jaiswal, Amit K., et al.
Publicado: (2016)

Nedaplatin/Peganum harmala Alkaloids Co-Loaded Electrospun, Implantable Nanofibers: A Chemopreventive Nano-Delivery System for Treating and Preventing Breast Cancer Recurrence after Tumorectomy
por: Sedky, Nada K., et al.
Publicado: (2023)

Formulation and Optimization of Oral Mucoadhesive Patches of Myrtus Communis by Box Behnken Design
por: Hashemi, Mahbubeh, et al.
Publicado: (2017)

Application of Box-Behnken Design in Production of Monoglyceride with Esterification of Glycerol and Oleic Acid
por: Neji, Soumaya Bouguerra, et al.
Publicado: (2023)

Statistical optimization of hyaluronic acid enriched ultradeformable elastosomes for ocular delivery of voriconazole via Box-Behnken design: in vitro characterization and in vivo evaluation
por: Fahmy, Abdurrahman Muhammad, et al.
Publicado: (2020)

Newly Synthesized Anticancer Purine Derivatives Inhibiting p-EIF4E Using Surface-Modified Lipid Nanovesicles
por: Attia, Reem T., et al.
Publicado: (2023)

SPME Method Optimized by Box-Behnken Design for Impact Odorants in Reduced Alcohol Wines
por: Saha, Bithika, et al.
Publicado: (2018)

Formulation Optimization and Assessment of Dexamethasone Orally Disintegrating Tablets Using Box-Behnken Design
por: Soroush, Hadis, et al.
Publicado: (2018)

Enhancing the Extraction of Phenolic Compounds from Juniper Berries Using the Box-Behnken Design
por: Elboughdiri, Noureddine, et al.
Publicado: (2020)

Box–Behnken Design: Optimization of Proanthocyanidin-Loaded Transferosomes as an Effective Therapeutic Approach for Osteoarthritis
por: Tamilarasan, Neelakandan, et al.
Publicado: (2022)

Pomegranate Flower Extract—The Health-Promoting Properties Optimized by Application of the Box–Behnken Design
por: Gościniak, Anna, et al.
Publicado: (2022)

Optimizing Catalytic Depolymerization of Lignin in Ethanol with a Day-Clustered Box–Behnken Design
por: Kouris, Panos D., et al.
Publicado: (2023)

Application of Box-Behnken design for optimization of phenolics extraction from Leontodon hispidulus in relation to its antioxidant, anti-inflammatory and cytotoxic activities
por: Abd-El-Aziz, Noha Mokhtar, et al.
Publicado: (2022)

Ultra-deformable liposomes containing terpenes (terpesomes) loaded fenticonazole nitrate for treatment of vaginal candidiasis: Box-Behnken design optimization, comparative ex vivo and in vivo studies
por: Albash, Rofida, et al.
Publicado: (2020)

Application of Box-Behnken Design in the Preparation, Optimization, and In-Vivo Pharmacokinetic Evaluation of Oral Tadalafil-Loaded Niosomal Film
por: Abla, Kawthar K., et al.
Publicado: (2023)

Evaluation of the effect of physical variables on in vitro release of diclofenac pellets using Box-Behnken design
por: Enayatifard, Reza, et al.
Publicado: (2015)

Formulation and optimization of itraconazole polymeric lipid hybrid nanoparticles (Lipomer) using box behnken design
por: Gajra, Balaram, et al.
Publicado: (2015)

Formulation And Evaluation Of Nanostructured Lipid Carriers (NLCs) Of 20(S)-Protopanaxadiol (PPD) By Box-Behnken Design
por: Kim, Min-Hwan, et al.
Publicado: (2019)

Insights from a Box–Behnken Optimization Study of Microemulsions with Salicylic Acid for Acne Therapy
por: Anicescu, Maria-Cristina, et al.
Publicado: (2022)

Betaine host–guest complexation with a calixarene receptor: enhanced in vitro anticancer effect
por: Fahmy, Sherif Ashraf, et al.
Publicado: (2021)

Formulation and Optimization of Polymeric Nanoparticles for Intranasal Delivery of Lorazepam Using Box-Behnken Design: In Vitro and In Vivo Evaluation
por: Sharma, Deepak, et al.
Publicado: (2014)

Development and statistical optimization of nefopam hydrochloride loaded nanospheres for neuropathic pain using Box–Behnken design
por: Sukhbir, S., et al.
Publicado: (2016)

Optimization of Chitosan–Alginate Microparticles for Delivery of Mangostins to the Colon Area Using Box–Behnken Experimental Design
por: Mulia, Kamarza, et al.
Publicado: (2020)

Preparation, Statistical Optimization and Characterization of Propolis-Loaded Solid Lipid Nanoparticles Using Box-Behnken Design
por: Taherzadeh, Sahar, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_599v5rpinpislf02ag8cg9fk9u