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Raptor mediates the selective inhibitory effect of cardamonin on RRAGC-mutant B cell lymphoma

BACKGROUND: mTORC1 (mechanistic target of rapamycin complex 1) is associated with lymphoma progression. Oncogenic RRAGC (Rag guanosine triphosphatase C) mutations identified in patients with follicular lymphoma facilitate the interaction between Raptor (regulatory protein associated with mTOR) and R...

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Detalles Bibliográficos
Autores principales: Liu, Ying, Zhu, Yanting, Chen, Huajiao, Zhou, Jintuo, Niu, Peiguang, Shi, Daohua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10521446/
https://www.ncbi.nlm.nih.gov/pubmed/37749558
http://dx.doi.org/10.1186/s12906-023-04166-7