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Raptor mediates the selective inhibitory effect of cardamonin on RRAGC-mutant B cell lymphoma
BACKGROUND: mTORC1 (mechanistic target of rapamycin complex 1) is associated with lymphoma progression. Oncogenic RRAGC (Rag guanosine triphosphatase C) mutations identified in patients with follicular lymphoma facilitate the interaction between Raptor (regulatory protein associated with mTOR) and R...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10521446/ https://www.ncbi.nlm.nih.gov/pubmed/37749558 http://dx.doi.org/10.1186/s12906-023-04166-7 |