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Inflammasome activation in peritumoral astrocytes is a key player in breast cancer brain metastasis development
Inflammasomes, primarily responsible for the activation of IL-1β, have emerged as critical regulators of the tumor microenvironment. By using in vivo and in vitro brain metastasis models, as well as human samples to study the role of the NLRP3 inflammasome in triple-negative breast cancer (TNBC) bra...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10521486/ https://www.ncbi.nlm.nih.gov/pubmed/37749707 http://dx.doi.org/10.1186/s40478-023-01646-2 |