Cargando…

Inflammasome activation in peritumoral astrocytes is a key player in breast cancer brain metastasis development

Inflammasomes, primarily responsible for the activation of IL-1β, have emerged as critical regulators of the tumor microenvironment. By using in vivo and in vitro brain metastasis models, as well as human samples to study the role of the NLRP3 inflammasome in triple-negative breast cancer (TNBC) bra...

Descripción completa

Detalles Bibliográficos
Autores principales: Mészáros, Ádám, Molnár, Kinga, Fazakas, Csilla, Nógrádi, Bernát, Lüvi, Adél, Dudás, Tamás, Tiszlavicz, László, Farkas, Attila Elek, Krizbai, István Adorján, Wilhelm, Imola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10521486/
https://www.ncbi.nlm.nih.gov/pubmed/37749707
http://dx.doi.org/10.1186/s40478-023-01646-2