Transcription factor E4F1 dictates spermatogonial stem cell fate decisions by regulating mitochondrial functions and cell cycle progression

BACKGROUND: Spermatogonial stem cells (SSCs) provide a foundation for robust and continual spermatogenesis in mammals. SSCs self-renew to maintain a functional stem cell pool and differentiate to supply committed progenitors. Metabolism acts as a crucial determinant of stem cell fates; however, fact...

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Detalles Bibliográficos
Autores principales: Yan, Rong-Ge, He, Zhen, Wang, Fei-Chen, Li, Shuang, Shang, Qin-Bang, Yang, Qi-En
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10521505/
https://www.ncbi.nlm.nih.gov/pubmed/37749649
http://dx.doi.org/10.1186/s13578-023-01134-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10521505/
https://www.ncbi.nlm.nih.gov/pubmed/37749649
http://dx.doi.org/10.1186/s13578-023-01134-z

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