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Transcription factor E4F1 dictates spermatogonial stem cell fate decisions by regulating mitochondrial functions and cell cycle progression
BACKGROUND: Spermatogonial stem cells (SSCs) provide a foundation for robust and continual spermatogenesis in mammals. SSCs self-renew to maintain a functional stem cell pool and differentiate to supply committed progenitors. Metabolism acts as a crucial determinant of stem cell fates; however, fact...
Autores principales: | Yan, Rong-Ge, He, Zhen, Wang, Fei-Chen, Li, Shuang, Shang, Qin-Bang, Yang, Qi-En |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10521505/ https://www.ncbi.nlm.nih.gov/pubmed/37749649 http://dx.doi.org/10.1186/s13578-023-01134-z |
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