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Stachydrine ameliorates hypoxia reoxygenation injury of cardiomyocyte via enhancing SIRT1-Nrf2 pathway

BACKGROUND: Hypoxia/reoxygenation (H/R)-induced cardiomyocyte cell apoptosis is critical in developing myocardial infarction. Stachydrine (STA), an active constituent of Leonurus heterophyllus sweet, could have a protective effect on myocardial H/R injury, which remains unexplored. Therefore, the st...

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Detalles Bibliográficos
Autores principales: Zhu, Xi, Wu, Yingbiao, Zhang, Xiaogang, Gu, Wei, Ning, Zhongping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10521545/
https://www.ncbi.nlm.nih.gov/pubmed/37752609
http://dx.doi.org/10.1186/s13019-023-02363-6