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Metformin induces ferroptosis through the Nrf2/HO-1 signaling in lung cancer

BACKGROUND: Metformin is the most frequently prescribed medication for the treatment of type II diabetes mellitus and has played an anti-tumor potential in a variety of cancer types. Metformin can inhibit the growth of many cancer cells through various mechanisms, including ferroptosis. However, it...

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Detalles Bibliográficos
Autores principales: Deng, Chengmin, Xiong, Lin, Chen, Yang, Wu, Kaifeng, Wu, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10521546/
https://www.ncbi.nlm.nih.gov/pubmed/37749553
http://dx.doi.org/10.1186/s12890-023-02655-6