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Efficient targeting of HIF-1α mediated by YC-1 and PX-12 encapsulated niosomes: potential application in colon cancer therapy

A number of molecular biofactors have been documented in pathogenesis and poor prognosis of colorectal cancer (CRC). Among them, the Hypoxia-Inducible Factor (HIF-1a) is frequently reported to become over-expressed, and its targeting could restrict and control a variety of essential hallmarks of CRC...

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Detalles Bibliográficos
Autores principales: Bakand, Azar, Moghaddam, Sevil Vaghefi, Naseroleslami, Maryam, André, Helder, Mousavi-Niri, Neda, Alizadeh, Effat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10521571/
https://www.ncbi.nlm.nih.gov/pubmed/37749603
http://dx.doi.org/10.1186/s13036-023-00375-3