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Cell Surface Platelet Tissue Factor Expression: Regulation by P2Y(12) and Link to Residual Platelet Reactivity

BACKGROUND: ADP-induced platelet activation leads to cell surface expression of several proteins, including TF (tissue factor). The role of ADP receptors in platelet TF modulation is still unknown. We aimed to assess the (1) involvement of P2Y(1) and P2Y(12) receptors in ADP-induced TF exposure; (2)...

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Detalles Bibliográficos
Autores principales: Brambilla, Marta, Becchetti, Alessia, Rovati, Gian Enrico, Cosentino, Nicola, Conti, Maria, Canzano, Paola, Giesen, Peter L.A., Loffreda, Alessia, Bonomi, Alice, Cattaneo, Marco, De Candia, Erica, Podda, Gian Marco, Trabattoni, Daniela, Werba, Pablo Josè, Campodonico, Jeness, Pinna, Christian, Marenzi, Giancarlo, Tremoli, Elena, Camera, Marina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10521789/
https://www.ncbi.nlm.nih.gov/pubmed/37589138
http://dx.doi.org/10.1161/ATVBAHA.123.319099